时间：2022年11月23日（周三）下午16:00-17:30

Time：16:00-17:30, Wednesday, Nov 23^rd, 2022

主持人: 西湖大学理学院PI 张鑫 教授

Host: Prof. Xin Zhang, PI of School of Science, Westlake University

地址：西湖大学云谷校区E10-201教室

Venue: E10-201, Yungu Campus, Westlake University

Prof. Peng Wu,

Professor of Department of Molecular Medicine, 

The Scripps Research Institute

主讲人简介/Biography:

Prof. Peng Wu received his doctorate from the Scripps Research Institute in 2005 under the guidance of Professor K. Barry Sharpless. From August 2005 to September 2008, he was a postdoctoral fellow in the group of Professor Carolyn R. Bertozzi at the University of California, Berkeley. There, he combined his interests in bioorthogonal chemistry and biotechnology by developing a method for site-specific modification of monoclonal antibodies using a genetically encoded aldehyde tag. The research in the Wu lab integrates synthetic chemistry with glycobiology to explore the cellular and molecular mechanisms that control immune responses toward cancer and human pathogens. He was awarded the ACS Horace S. Isbell Award in 2020, the RSC Horizon Prize in 2021 and the SFG Glycobiology Significant Achievement Award in 2021.

讲座摘要/Abstract:

We know little about the precise contributions of endogenous antigen-specific and bystander T cells during the course of a natural pathogen infection and cancer progression. Due to their heterogeneous compositions, it is challenging to elucidate their properties. Through detecting endogenous antigen-specific T cells and separating them from bystander T cells, the Wu lab has made progress in understanding the specific roles and functional differences of these two T-cell subsets in an immune response, how T cells’ reactivity is linked to their functional state, and how to improve persistence and replication potential of antigen-specific T cells for treating infection and cancer.

讲座联系人/Contact:

理学院，梁子微，邮箱：liangziwei@westlake.edu.cn

School of Science, Ziwei Liang, Email: liangziwei@westlake.edu.cn